{"id":394,"date":"2025-01-31T09:59:54","date_gmt":"2025-01-31T01:59:54","guid":{"rendered":"http:\/\/192.168.6.218\/?p=394"},"modified":"2026-07-17T11:28:50","modified_gmt":"2026-07-17T03:28:50","slug":"2025-1-31","status":"publish","type":"post","link":"https:\/\/www.trx.com.tw\/en\/2025-1-31\/","title":{"rendered":"\u53f0\u777f\u65b0\u85e5CVM-1118\u53d6\u5f97\u80f0\u817a\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624(PNETs)\u5b64\u5152\u85e5\u8cc7\u683c\uff0c\u672a\u4f86\u4e0a\u5e02\u4eab\u7f8e\u570b7\u5e74\u5e02\u5834\u5c08\u8ce3\u7368\u4f54\u6b0a"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u53f0\u777f\u7814\u767c\u7684\u53e3\u670d\u6297\u764c\u65b0\u85e5 CVM-1118 (Foslinanib)\u65bc2025\u5e741\u670831\u65e5\u7372\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40(FDA)\u6b63\u5f0f\u6388\u4e88\u80f0\u817a\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624 (Pancreatic Neuroendocrine Tumors, PNETs) \u9069\u61c9\u75c7\u7684\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a(Orphan Drug Designation)\uff0c\u672a\u4f86CVM-1118 \u7372\u5f97\u4e0a\u5e02\u8a31\u53ef\u5f8c\uff0c\u5c07\u4eab\u6709\u4e03\u5e74\u7684\u7f8e\u570b\u5e02\u5834\u5c08\u8ce3\u7368\u5360\u6b0a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u80f0\u81df\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624( PNETs) \u70ba\u7f55\u898b\u7684\u80f0\u81df\u816b\u7624\uff0c\u81f3\u4eca\u70ba\u6b62\u5176\u5728\u7f8e\u570b\u7684\u60a3\u75c5\u7387\u4f4e\u65bc 20 \u842c\u4eba\uff0c\u5c40\u90e8\u3001\u5340\u57df\u548c\u8f49\u79fb\u6027\u816b\u7624\u76845\u5e74\u7e3d\u751f\u5b58\u7387\u5206\u5225\u70ba83%\u300167%\u548c28%\uff0c\u4f46\u591a\u6578\u75c5\u4eba\u88ab\u8a3a\u65b7\u6642\u5df2\u7d93\u767c\u73fe\u6709\u8f49\u79fb\uff0c\u53ea\u80fd\u9078\u64c7\u9ad4\u6291\u7d20\u985e\u4f3c\u7269\u85e5\u7269\u7642\u6cd5\u3001\u53e3\u670d\u6a19\u9776\u85e5\u7269\u53ca\u50b3\u7d71\u5316\u5b78\u6cbb\u7642\uff0c\u53ef\u9078\u64c7\u7684\u6cbb\u7642\u85e5\u7269\u4e0d\u591a\uff0c\u9810\u5f8c\u76f8\u5c0d\u8f03\u5dee\u3002\u6839\u64daData Bridge Market Research (2023) \u5206\u6790\u6307\u51fa\uff0c2023\u5e74\u5168\u7403\u795e\u7d93\u5167\u5206\u6ccc\u764c\u5e02\u5834\u898f\u6a21\u70ba32.3\u5104\u7f8e\u5143\uff0c\u9810\u8a08\u52302031\u5e74\u5c07\u9054\u523071.3\u5104\u7f8e\u5143\uff0c2024-2031\u5e74\u8907\u5408\u6210\u9577\u7387\u70ba10.4%\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CVM-1118(Foslinanib)\u662f\u4e00\u7c92\u7dda\u9ad4\u86cb\u767dTRAP1\u6291\u5236\u5291\uff0c\u540c\u6642\u5177\u6709\u4fc3\u9032\u7d30\u80de\u51cb\u4ea1\u3001\u6291\u5236\u816b\u7624\u751f\u9577\u53ca\u816b\u7624\u985e\u7ba1\u9053\u5f62\u6210 (vasculogenic mimicry ,VM)\u4e4b\u7279\u6027\uff0c\u81e8\u5e8a\u524d\u80f0\u817a\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u52d5\u7269\u6a21\u578b\u4e2d\u8b49\u5be6CVM-1118\u5177\u6709\u6297\u764c\u6d3b\u6027\uff0c\u9032\u4e00\u6b65\u5728\u4e8c\u671f\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\u4e2d(CVM-005)\u8b49\u5be6 CVM-1118 \u4e0d\u50c5\u5b89\u5168\u6027\u4f73\uff0c\u4ea6\u80fd\u5ef6\u9577 PNET 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